Ovarian Reserve Profile Advanced (ORP Advanced) Test: Booking, Price, and Results
About Ovarian Reserve Profile Advanced (ORP Advanced) Test
| Field | Value |
|---|---|
| Also Known As | Advanced Ovarian Reserve Profile, Comprehensive Ovarian Reserve Panel, Fertility Reserve Panel, Multimarker Ovarian Reserve Assessment |
| Sample Type | Venous blood |
| Fasting Required | No fasting required |
| Report Time | 24 to 48 hours |
| Recommended For | Women of reproductive age (typically 18 to 45 years) |
| Price | Starting at ₹5,000 |
What Is an Ovarian Reserve Profile Advanced (ORP Advanced) Test?
The ORP advanced test is a blood-based fertility assessment that measures multiple hormones linked to egg supply and ovarian function. Doctors typically recommend this test for women who are planning a pregnancy, experiencing difficulty conceiving, or undergoing fertility treatment such as IVF. Also known as the Advanced Ovarian Reserve Profile or Fertility Reserve Panel, it provides a broader picture of reproductive health than a single-hormone test alone.
What Does an Ovarian Reserve Profile Advanced (ORP Advanced) Test Measure?
This comprehensive ovarian reserve assessment analyses five key reproductive hormones from a single blood sample. Together, they give a fuller view of how many eggs remain and how well the ovaries are functioning.
Here is a brief overview of each parameter measured:
| Parameter | What It Reflects |
|---|---|
| Anti-Müllerian Hormone (AMH) | Produced by ovarian follicles (the tiny sacs that contain eggs); higher levels suggest a larger egg supply, lower levels suggest a smaller one |
| Follicle Stimulating Hormone (FSH) | Released by the pituitary gland in the brain to stimulate egg growth; raised levels on Day 3 of the cycle may suggest reduced egg supply |
| Luteinising Hormone (LH) | A pituitary hormone that triggers ovulation; an imbalance between LH and FSH can point to conditions such as PCOS (polycystic ovary syndrome) |
| Oestradiol (E2) | The primary oestrogen produced by the ovaries, measured on Day 3, to help interpret FSH results and assess ovarian activity |
| Inhibin B | A reproductive hormone that provides additional information about egg supply and is useful in assessing fertility |
Why Is an Ovarian Reserve Profile Advanced (ORP Advanced) Test Done?
An advanced fertility reserve testing panel is ordered for several reasons, from investigating fertility concerns to guiding treatment decisions.
Common Symptoms That May Require This Test
- Difficulty conceiving after regular, unprotected intercourse
- Irregular or absent menstrual periods
- A noticeably shorter menstrual cycle than before
- Hot flushes or night sweats in women under 40
- Vaginal dryness not explained by other causes
- Heavier-than-usual menstrual bleeding
- Missed periods without an obvious reason
Conditions This Test Can Help Detect
This advanced ovarian reserve evaluation can help identify or rule out several conditions:
- Diminished ovarian reserve: Where fewer eggs remain than expected for your age
- Primary ovarian insufficiency: Sometimes called early menopause, occurring before age 40
- Polycystic ovary syndrome (PCOS): Which is often associated with elevated AMH levels
- Granulosa cell tumours, a rare type of ovarian tumour
- Poor or excessive response to IVF stimulation before treatment begins
- Approaching natural menopause
How to Prepare and What to Expect
Preparing for this integrated ovarian reserve screening panel is straightforward. Here is what you need to know before your appointment.
Do You Need to Fast?
No fasting is required for this test. You may eat and drink normally on the day of your blood draw. AMH can be measured on any day of your menstrual cycle, but FSH, LH, and oestradiol are best collected between Days 2 and 5 of your cycle for the most meaningful results.
Practical Tips Before Your Test
- Schedule your appointment for Days 2 to 5 of your menstrual cycle if possible
- Tell your doctor if you are currently using hormonal contraceptives, as these can influence AMH readings
- Inform your doctor about any other medications or supplements you are taking
- Drink adequate water to keep the veins accessible for the blood draw
- Avoid strenuous exercise immediately before your appointment
Step-by-Step Procedure
- A trained phlebotomist will clean the skin on your inner arm with an antiseptic solution.
- A soft elastic band is placed around your upper arm to make the vein easier to locate.
- A sterile needle is gently inserted into a vein to draw a small blood sample.
- The blood is collected into the appropriate laboratory tubes.
- The needle is removed, and light pressure is applied to the site to stop any bleeding.
- Your sample is labelled and dispatched to the laboratory for analysis.
Factors That Can Affect Accuracy
- Age, as AMH levels decline naturally over time
- PCOS, which tends to elevate AMH significantly
- Prior ovarian surgery, such as cyst removal, which can reduce AMH
- Hormonal contraceptive use, which may lower AMH readings
- Smoking and obesity, both of which are associated with lower AMH levels
Understanding Your Ovarian Reserve Profile Advanced (ORP Advanced) Test Results
Your results should always be reviewed alongside your full medical history. The table below shows general reference ranges for each parameter.
| Parameter | Reference Range | Unit |
|---|---|---|
| AMH (reproductive age) | 1.0 to 4.0 (optimal); below 1.0 suggests low reserve | ng/mL |
| FSH (Day 3, follicular phase) | 3 to 10 (normal); above 10 to 12 suggests reduced reserve | mIU/mL |
| LH (follicular phase) | 1.1 to 11.6 | mIU/mL |
| Oestradiol (Day 3) | 25 to 75 (ideal); above 80 may indicate an issue | pg/mL |
| Inhibin B | >45 (normal function); <45 (Diminished ovarian reserve) | pg/mL |
These ranges are general guidelines. Your doctor will interpret your results based on your age, health history, and other factors. Always consult a qualified healthcare professional for personalised medical advice.
Results During Special Conditions
- Long-term use of oral contraceptives is associated with a moderate, reversible decrease in ovarian reserve markers.
- Smoking has been linked to faster AMH decline and earlier onset of menopause.
- Obesity can also influence AMH readings.
- Any prior surgery on the ovaries may reduce AMH levels independently of your natural reserve.
How to Maintain Healthy Levels
- Maintain a healthy weight, as obesity is associated with lower AMH and poorer egg quality
- Avoid smoking, which is linked to an accelerated egg supply decline
- Include nutrient-rich foods in your diet, such as fatty fish (rich in omega-3 fatty acids), fortified dairy (a source of vitamin D), and berries (which contain antioxidants)
- Limit alcohol consumption to support hormonal balance
Lupin Diagnostics Ovarian Reserve Profile Advanced (ORP Advanced) Test Price and Home Collection
The ORP advanced test is available at Lupin Diagnostics centres and through home collection. Prices start at approximately ₹5,000, depending on your city. The table below shows indicative prices across major cities in India:
| City | Approximate Price (₹) |
|---|---|
| Mumbai | ₹5,900 |
| Delhi/NCR | ₹5,900 |
| Bengaluru | ₹5,900 |
| Hyderabad | ₹5,000 |
| Chennai | ₹5,500 |
| Kolkata | ₹5,900 |
| Pune | ₹5,900 |
| Ahmedabad | ₹5,500 |
Prices are indicative and may vary by location. Please confirm the current price at the time of booking.
How to Book
- Select the test on the Lupin Diagnostics website.
- Choose your city and preferred time slot.
- Opt for home sample collection by a certified phlebotomist, or visit your nearest Lupin Diagnostics centre.
- Receive your report via email or WhatsApp within the stipulated turnaround time.
Home Collection
Lupin Diagnostics offers home sample collection for this test across cities in India. All samples are processed in NABL-accredited laboratories by experienced technologists, ensuring accuracy and reliability. Your digital report is delivered directly to your email or WhatsApp, making access quick and convenient.
Frequently Asked Questions
FSH, LH, and oestradiol should ideally be collected on Days 2 to 5 of your menstrual cycle for the most accurate reading. AMH, however, can be measured on any day of your cycle. If you are unsure when to book, your doctor can guide you based on your individual cycle pattern.
No. This advanced ovarian reserve evaluation estimates your egg supply and your ovaries' response to fertility treatment. It does not assess egg quality or predict the likelihood of a successful pregnancy. For a full picture of your fertility, your doctor will consider this test alongside other assessments.
A low AMH level suggests that your remaining egg supply is smaller than expected for your age. This does not mean pregnancy is impossible, but it may affect how your body responds to fertility treatments. Your doctor will discuss your options based on the complete panel results.
No fasting is needed. You can eat and drink as normal before your blood draw.
Yes, they may. Long-term use of hormonal contraceptives has been associated with a moderate, reversible reduction in ovarian reserve markers such as AMH. Always inform your doctor if you are currently using or have recently stopped hormonal contraception.
A small blood sample is drawn from a vein in your arm. The process takes only a few minutes and causes minimal discomfort. If you opt for home collection, a trained phlebotomist will visit at your chosen time.
Not always. While higher AMH generally points to a larger egg supply, very high levels can be associated with PCOS, a condition where many small follicles develop, but regular ovulation may be disrupted. Your doctor will interpret your AMH result alongside FSH, LH, and oestradiol to give a complete picture.
Ovarian Reserve Profile Advanced (ORP Advanced) Test: Booking, Price, and Results
