Mycoplasma Pneumoniae IgG Antibody Test: Booking, Price, and Results
About Mycoplasma Pneumoniae IgG Antibody Test
| Field | Value |
|---|---|
| Also Known As | M. pneumoniae IgG, Mycoplasma Serology, Mycoplasma Antibody Test, M. pneumoniae Ab |
| Sample Type | Venous blood (serum) |
| Fasting Required | No fasting required |
| Report Time | 2 to 5 days |
| Recommended For | All ages, male and female; commonly ordered for children and young adults |
| Price | Starting at ₹2,600 |
What Is a Mycoplasma Pneumoniae, IgG Antibody Test?
The Mycoplasma pneumoniae, IgG Antibody Test checks whether your blood contains IgG antibodies against Mycoplasma pneumoniae, a bacterium that can cause respiratory illness. IgG antibodies are proteins produced by your immune system in response to infection, and their presence shows that your body has encountered this bacterium at some point. The test uses a blood (serum) sample and is also referred to as M. pneumoniae IgG, Mycoplasma Serology, or the Mycoplasma Antibody Test. Doctors often order it alongside an IgM antibody test for a fuller picture of infection timing.
What Does a Mycoplasma Pneumoniae, IgG Antibody Test Measure?
This test detects a single immune marker in your blood. The table below explains what it measures and what the result indicates.
| Parameter | What It Measures |
|---|---|
| M. pneumoniae IgG | IgG antibodies produced by the immune system in response to past or prolonged exposure to M. pneumoniae |
A positive M. pneumoniae IgG result shows that your body has been exposed to this bacterium before. It does not, on its own, confirm a current active infection. To determine whether an infection is recent, doctors typically look at IgM antibody levels or compare two blood samples taken a few weeks apart.
Why Is a Mycoplasma Pneumoniae, IgG Antibody Test Done?
This test is ordered when a doctor suspects a Mycoplasma pneumoniae infection or wants to investigate past exposure. It plays a useful role in diagnosing both common and less typical presentations of respiratory illness.
Common Symptoms That May Require This Test
A doctor may request this test if you present with any of the following symptoms:
- Persistent dry cough that does not resolve quickly
- Fever, particularly in children or young adults
- Difficulty breathing or shortness of breath
- Sore throat or throat discomfort
- Unexplained fatigue or general weakness
- Headache alongside respiratory symptoms
- Chest discomfort or tightness
Conditions This Test Can Help Detect
Mycoplasma Serology testing can support the diagnosis of several conditions, including:
- Atypical pneumonia, often called "walking pneumonia," where symptoms are milder than typical pneumonia
- Upper respiratory infections such as pharyngitis (throat infection) and tracheobronchitis (inflammation of the windpipe and airways)
- Community-acquired pneumonia, as M. pneumoniae is linked to roughly 20% of such cases
- Extrapulmonary (non-lung) complications such as haemolytic anaemia (breakdown of red blood cells), joint inflammation, liver-related disease, cardiac involvement, and certain skin rashes
How to Prepare and What to Expect
No special preparation is needed for this test. Here is what you should know before your appointment.
Do You Need to Fast?
No, fasting is not required before the Mycoplasma pneumoniae, IgG Antibody Test. You can eat and drink normally on the day of collection. If your doctor has requested additional tests at the same time, check whether any of those tests require fasting.
Practical Tips Before Your Test
Keep these points in mind before your sample is collected:
- Eat and drink normally; there are no dietary restrictions for this test
- Drink adequate water before the blood draw to make vein access easier
- Inform your healthcare provider about any medications you are taking
- If you have a condition that affects your immune system, or take medicines that suppress immunity, let your doctor know before the test
Step-by-Step Procedure
Here is what happens during sample collection:
- A trained phlebotomist cleans the inside of your arm with an antiseptic wipe.
- A small needle is inserted into a vein, and blood is collected into a tube. The discomfort is brief.
- Once drawn, the needle is removed and a cotton swab or bandage is placed over the puncture site.
- The laboratory separates the serum (the liquid part of blood) from the cells, ideally within two hours of collection.
- The serum sample is tested for M. pneumoniae IgG antibodies using techniques such as ELISA or immunofluorescence.
- The sample is processed and your result is prepared within two to five days.
Factors That Can Affect Accuracy
Several factors may influence the accuracy of your result:
- Timing of the blood draw: antibodies may not be detectable in very early infection
- A weakened immune system due to illness or medication, which may reduce antibody production
- Recent antibiotic use before the test
- Cross-reactivity with related bacteria, which can occasionally produce a false positive result
Understanding Your Mycoplasma Pneumoniae, IgG Antibody Test Results
Your result will fall into one of three categories based on the measured antibody level. Always review your result with your doctor, who will consider your symptoms and medical history alongside the numbers.
| Result | IgG Value (U/L) | Interpretation |
|---|---|---|
| Negative | Less than 0.10 | No detectable antibodies; no evidence of prior exposure |
| Equivocal | 0.10 to 0.32 | Borderline result; repeat testing may be needed |
| Positive | Greater than 0.32 | Antibodies detected; indicates past or prior exposure |
These ranges are general guidelines. Your doctor will interpret your results based on your age, health history, and other factors. Always consult a qualified healthcare professional for personalised medical advice.
Results During Special Conditions
Certain health states can affect how reliable your result is. Patients with a weakened immune system (immunocompromised individuals) may produce lower-than-expected antibody levels, leading to a false-negative result. For this reason, M. pneumoniae Ab interpretation in people who are immunocompromised or in newborns requires extra caution, as the reliability of this test has not been fully established in those groups. Additionally, cross-reactivity with related organisms may occasionally cause a false-positive reading.
How to Maintain General Wellness
While this test measures past exposure rather than an ongoing health metric, good respiratory hygiene reduces your risk of respiratory infections in general:
- Cover your mouth and nose when coughing or sneezing, and encourage others around you to do the same
- Wash your hands regularly, especially after being in schools, public transport, or crowded spaces
- Avoid close contact with people who have active respiratory illness
Lupin Diagnostics Mycoplasma Pneumoniae, IgG Antibody Test Price and Home Collection
The Mycoplasma pneumoniae, IgG Antibody Test is available at Lupin Diagnostics with home blood collection across major cities. The table below shows indicative prices across major cities in India:
| City | Approximate Price (₹) |
|---|---|
| Mumbai | ₹2,600 |
| Bengaluru | ₹2,600 |
| Chennai | ₹2,600 |
| Hyderabad | ₹2,600 |
| Kolkata | ₹2,600 |
| Pune | ₹2,600 |
Prices are indicative and may vary by location. Please confirm the current price at the time of booking.
How to Book
- Select the test on the Lupin Diagnostics website.
- Choose your city and preferred time slot.
- Opt for home sample collection by a certified phlebotomist, or visit your nearest Lupin Diagnostics centre.
- Receive your report via email or WhatsApp within the stipulated turnaround time.
Home Collection
Lupin Diagnostics offers home sample collection across cities, so you can have your blood drawn at a time that suits you. All samples are processed in NABL-accredited laboratories by trained professionals. Your digital report is delivered directly to you via email or WhatsApp once ready.
Frequently Asked Questions
IgM antibodies appear first after an infection and are a sign of a recent or active encounter with the bacterium. M. pneumoniae IgG antibodies develop later and can stay in the body for months or even years after the infection has resolved. In short, IgM points to current infection, while IgG reflects past exposure.
Yes. A positive M. pneumoniae IgG result simply means your body has been exposed to Mycoplasma pneumoniae at some point. IgG antibodies can remain elevated long after an infection clears, and many healthy adults have detectable levels with no active symptoms at all.
When a single result is unclear, comparing two blood samples drawn one to three weeks apart can help. A significant rise in M. pneumoniae Ab levels between the two samples is a stronger indicator of a recent or returning infection than one sample alone.
The Mycoplasma pneumoniae, Antibody Test for IgG tells you about past exposure, not necessarily current illness. For confirming an active infection, molecular testing (PCR) is the preferred method. Your doctor will decide which test or combination of tests is most appropriate for your situation.
IgG antibodies generally develop within two weeks of infection. Once they appear, they can remain detectable in the blood for several months or longer, which is why a positive result does not always mean you are currently unwell.
Mycoplasma Serology testing has some known limitations. Antibodies may not be detectable if blood is drawn very early in the infection. In people with weakened immune systems, antibody production can be reduced, making results harder to interpret. Cross-reactivity with other organisms can also occasionally affect accuracy.
Mycoplasma pneumoniae infections are most common in children of school age and young adults. People who spend time in crowded settings such as schools, hostels, or shelters face a higher chance of exposure. The infection can affect any age group, though, and mild cases are often mistaken for a common cold or mild chest illness.




